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Age-tailored artificial skin model for cosmetic film development
  • Gonçalves, Marta ;
  • Brito, Sofia ;
  • Song, Chaeyeon ;
  • Han, Youngkyu ;
  • Bin, Bum Ho ;
  • Weon, Byung Mook
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Publication Year
2025-04-01
Journal
Materials Today Bio
Publisher
Elsevier B.V.
Citation
Materials Today Bio, Vol.31
Keyword
Aging skinArtificial skinBiomimeticsCosmeticSoft materialsThin film
Mesh Keyword
Aging skinArtificial skinArtificial skin modelCosmetic industryFilm developmentSkin topographySofter materialsThin-film depositionsThin-filmsUniform layer
All Science Classification Codes (ASJC)
BiotechnologyBioengineeringBiomaterialsBiomedical EngineeringMolecular BiologyCell Biology
Abstract
Thin film deposition is essential in the cosmetic industry, where formulations such as foundations and concealers rely on uniform layer formation to conceal pores and texture irregularities for a natural and even appearance. However, variations in skin topography, influenced by factors such as aging, genetics, and environmental exposure, can significantly affect the behavior of these films. Aging, in particular, leads to increased skin roughness and wrinkles, creating challenges to achieve consistent cosmetic deposition in diverse age groups. This study investigates the impact of age-related topographical changes on cosmetic thin film deposition and introduces a model for standardized, age-specific evaluation of cosmetic performance. Using X-ray microtomography, we compare skin topography from a cohort of the Korean population segmented into young and aged groups. A PDMS-based model is then constructed using these skin topographies, and thin film deposition is assessed both on human-derived skin positives and on the assembled model. This approach demonstrates the potential of artificial skin models for the precise quantification and evaluation of film coverage. In addition, we propose an improved model that incorporates key factors such as skin porosity and sebum production to increase realism. By exploring the interactions between skin morphology and cosmetic behavior, this method offers valuable insights into optimizing formulations to meet the diverse needs of consumers.
ISSN
2590-0064
Language
eng
URI
https://aurora.ajou.ac.kr/handle/2018.oak/38521
https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85218988265&origin=inward
DOI
https://doi.org/10.1016/j.mtbio.2025.101618
Journal URL
https://www.sciencedirect.com/science/journal/25900064
Type
Article
Funding
This research has been supported by AMOREPACIFIC and by Yangyoung Foundation in 2024. Additionally, this work was supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIT) (No. RS-2024-00405818) and funded by the Ministry of Education (2019R1A6A1A0303321522).
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Bin, Bum-Ho빈범호
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