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A washing-free immunoassay platform based on the passive movement of retroreflective micro particle and image processing
  • Kim, Ka Ram ;
  • Chun, Hyeong Jin ;
  • Jeong, Kwan Young ;
  • Kim, Jae Ho ;
  • Yoon, Hyun C.
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dc.contributor.authorKim, Ka Ram-
dc.contributor.authorChun, Hyeong Jin-
dc.contributor.authorJeong, Kwan Young-
dc.contributor.authorKim, Jae Ho-
dc.contributor.authorYoon, Hyun C.-
dc.date.issued2018-01-01-
dc.identifier.urihttps://aurora.ajou.ac.kr/handle/2018.oak/36352-
dc.identifier.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85079897767&origin=inward-
dc.description.abstractIn this study, washing-free immunoassay platform on retroreflective optical setup with precise signal distinguishable image processing was established and evaluated for cardiac troponin I. Washing-free immunoassay was enabled due to the passive movement, which is sedimentation property in direction of gravity, of retroreflective Janus particles as time went by. During the assay, sedimentation direction was controlled by simple inverting of the fluidic channel and unreacted RJP would remove by its own specific gravity. In addition, to ensure accuracy, the image processing of time-lapse images were applied to eliminate false signals caused by non-specific binding.-
dc.description.sponsorshipThis research was supported by the Samsung Research Funding Center of Samsung Electronics under the Project Number SRFC-IT1401-51.-
dc.description.sponsorshipThis research was supported by the Project Number SRFC-IT1401-51.-
dc.language.isoeng-
dc.publisherChemical and Biological Microsystems Society-
dc.subject.meshCardiac troponin-
dc.subject.meshFluidic channels-
dc.subject.meshJanus particles-
dc.subject.meshMicro particles-
dc.subject.meshNon-specific binding-
dc.subject.meshOptical bio-sensors-
dc.subject.meshPassive movement-
dc.subject.meshTime lapse images-
dc.titleA washing-free immunoassay platform based on the passive movement of retroreflective micro particle and image processing-
dc.typeConference-
dc.citation.conferenceDate2018.11.11. ~ 2018.11.15.-
dc.citation.conferenceName22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018-
dc.citation.edition22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018-
dc.citation.endPage818-
dc.citation.startPage816-
dc.citation.title22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018-
dc.citation.volume2-
dc.identifier.bibliographicCitation22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018, Vol.2, pp.816-818-
dc.identifier.doi2-s2.0-85079897767-
dc.identifier.scopusid2-s2.0-85079897767-
dc.subject.keywordImage processing-
dc.subject.keywordRetroreflective optical biosensor-
dc.subject.keywordWashing-free immunoassay-
dc.type.otherConference Paper-
dc.subject.subareaChemistry (all)-
dc.subject.subareaBioengineering-
dc.subject.subareaChemical Engineering (miscellaneous)-
dc.subject.subareaControl and Systems Engineering-
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