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Association between Long-Term Exposure to Fine Particulate Matter and Asthma Incidence among School-Aged Childrenoa mark
  • Lim, Hyun Mook ;
  • Ryoo, Seung Woo ;
  • Hong, Yun Chul ;
  • Kim, Soon Tae ;
  • Lim, Youn Hee ;
  • Lee, Dong Wook
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dc.contributor.authorLim, Hyun Mook-
dc.contributor.authorRyoo, Seung Woo-
dc.contributor.authorHong, Yun Chul-
dc.contributor.authorKim, Soon Tae-
dc.contributor.authorLim, Youn Hee-
dc.contributor.authorLee, Dong Wook-
dc.date.issued2022-09-01-
dc.identifier.issn2073-4433-
dc.identifier.urihttps://aurora.ajou.ac.kr/handle/2018.oak/32952-
dc.identifier.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85138736264&origin=inward-
dc.description.abstractStudies on the correlation of long-term PM2.5 exposure with childhood-onset asthma are limited to western countries. We aimed to study the association between long-term PM2.5 exposure and childhood-onset asthma in South Korea, which has higher ambient PM2.5 levels than western countries. We constructed a retrospective cohort of children aged 6–14 years living in seven metropolitan cities using the National Health Insurance service in South Korea from 2011 to 2016. Children who made a hospital visit with asthma from 2008 to 2010 were excluded. A child was diagnosed with asthma incidence if he or she visited the hospital three times or more with a primary diagnostic code of asthma. A time-varying Cox regression model was constructed to investigate the association of long-term district-level PM2.5 exposure with asthma incidence. Of the 1,425,638 children evaluated, 52,133 showed asthma incidence, with an incidence rate of 6.9 cases/1000 person-years. A 10 µg/m3 increase in the 48-month moving average PM2.5 exposure was associated with an elevated risk of asthma incidence, with a hazard ratio of 1.075 (95% confidence interval: 1.024–1.126), and this association was robust for different PM2.5 exposure levels (12-, 36-, and 60-month moving average). In this study, long-term exposure to PM2.5 was associated with asthma incidence in school-aged children in South Korea. Policies to reduce environmental PM2.5 levels and protect children from PM2.5 are necessary to prevent childhood-onset asthma.-
dc.description.sponsorshipThis study used the customized Health Insurance Data based on health insurance claims data in Korea. The aim and conclusion of this study are irrelevant to the National Health Insurance Service, Republic of Korea. The research number of this study is NHIS-2019-1-023. This research was supported by the Seoul St. Mary\u2019s Hospital\u2019s Environmental Health Center for Training Environmental Medicine Professionals funded by the Ministry of Environment, Republic of Korea (2021).-
dc.language.isoeng-
dc.publisherMDPI-
dc.subject.meshAsthma-
dc.subject.meshChild-
dc.subject.meshCohort studies-
dc.subject.meshFine particulate matter-
dc.subject.meshLong term exposure-
dc.subject.meshMoving averages-
dc.subject.meshParticulate Matter-
dc.subject.meshPM 2.5-
dc.subject.meshSouth Korea-
dc.subject.meshWestern countries-
dc.titleAssociation between Long-Term Exposure to Fine Particulate Matter and Asthma Incidence among School-Aged Children-
dc.typeArticle-
dc.citation.number9-
dc.citation.titleAtmosphere-
dc.citation.volume13-
dc.identifier.bibliographicCitationAtmosphere, Vol.13 No.9-
dc.identifier.doi10.3390/atmos13091430-
dc.identifier.scopusid2-s2.0-85138736264-
dc.identifier.urlwww.mdpi.com/journal/atmosphere-
dc.subject.keywordasthma-
dc.subject.keywordchildren-
dc.subject.keywordcohort study-
dc.subject.keywordlong-term exposure-
dc.subject.keywordparticulate matter-
dc.type.otherArticle-
dc.description.isoatrue-
dc.subject.subareaEnvironmental Science (miscellaneous)-
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