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Relation between blood pressure and pulse wave velocity for human arteriesoa mark
  • Ma, Yinji ;
  • Choi, Jungil ;
  • Hourlier-Fargette, Aurélie ;
  • Xue, Yeguang ;
  • Chung, Ha Uk ;
  • Lee, Jong Yoon ;
  • Wang, Xiufeng ;
  • Xie, Zhaoqian ;
  • Kang, Daeshik ;
  • Wang, Heling ;
  • Han, Seungyong ;
  • Kang, Seung Kyun ;
  • Kang, Yisak ;
  • Yu, Xinge ;
  • Slepian, Marvin J. ;
  • Raj, Milan S. ;
  • Model, Jeffrey B. ;
  • Feng, Xue ;
  • Ghaffari, Roozbeh ;
  • Rogers, John A. ;
  • Huang, Yonggang
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Publication Year
2018-10-30
Journal
Proceedings of the National Academy of Sciences of the United States of America
Publisher
National Academy of Sciences
Citation
Proceedings of the National Academy of Sciences of the United States of America, Vol.115 No.44, pp.11144-11149
Keyword
Arterial stiffnessArtery hyperelastic modelBlood pressureHemodynamicsPulse wave velocity
Mesh Keyword
ArteriesBlood Flow VelocityBlood PressureBlood Pressure DeterminationElectrocardiographyHumansMonitoring, PhysiologicPulsatile FlowPulse Wave Analysis
All Science Classification Codes (ASJC)
Multidisciplinary
Abstract
Continuous monitoring of blood pressure, an essential measure of health status, typically requires complex, costly, and invasive techniques that can expose patients to risks of complications. Continuous, cuffless, and noninvasive blood pressure monitoring methods that correlate measured pulse wave velocity (PWV) to the blood pressure via the Moens-Korteweg (MK) and Hughes Equations, offer promising alternatives. The MK Equation, however, involves two assumptions that do not hold for human arteries, and the Hughes Equation is empirical, without any theoretical basis. The results presented here establish a relation between the blood pressure P and PWV that does not rely on the Hughes Equation nor on the assumptions used in the MK Equation. This relation degenerates to the MK Equation under extremely low blood pressures, and it accurately captures the results of in vitro experiments using artificial blood vessels at comparatively high pressures. For human arteries, which are well characterized by the Fung hyperelastic model, a simple formula between P and PWV is established within the range of human blood pressures. This formula is validated by literature data as well as by experiments on human subjects, with applicability in the determination of blood pressure from PWV in continuous, cuffless, and noninvasive blood pressure monitoring systems.
ISSN
1091-6490
Language
eng
URI
https://aurora.ajou.ac.kr/handle/2018.oak/30434
https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85055649469&origin=inward
DOI
https://doi.org/2-s2.0-85055649469
Journal URL
http://www.pnas.org/content/pnas/115/44/11144.full.pdf
Type
Article
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