Ir(triNHC) complexes catalyzed glycerol and alcohol dehydrogenative coupling, yielding diverse α-hydroxy acids. Unlike conventional conditions, Ir(triNHC) facilitated additional C-C bond formation after lactic acid production from glycerol, exhibiting high TOFs. This protocol successfully converted 1,2-propanediol and sorbitol into α-hydroxy acids, highlighting biomass-derived sources’ potential as valuable platform chemicals.
This study was supported by the Carbon to X Program (No. 2020M3H7A1098283) and National Research Foundation Program (No. 2022R1A2C1004387) by the Ministry of Science and ICT, and the H2KOREA funded by the Ministry of Education (2022Hydrogen fuel cell-002), Innovative Human Resources Development Project for Hydrogen Fuel Cells.
