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Structure preserving t-SNE of matrix framed data
  • Ahn, Soohyun ;
  • Lim, Johan ;
  • Jiang, Wei ;
  • Lee, Sungim ;
  • Wang, Xinlei
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Publication Year
2025-01-01
Journal
Computational and Structural Biotechnology Journal
Publisher
Elsevier B.V.
Citation
Computational and Structural Biotechnology Journal, Vol.27, pp.1614-1635
Keyword
Bi-clusteringDimension reductionExergame dataMatrix t-SNEMicroarray gene expression data
Mesh Keyword
BiclusteringData elementsDimension reductionExergame dataExergamesGroup structurematrixMatrix t-SNEMicroarray gene expression dataStructure-preserving
All Science Classification Codes (ASJC)
BiotechnologyBiophysicsStructural BiologyBiochemistryGeneticsComputer Science Applications
Abstract
Across various fields, we can align data elements into a matrix frame with both row and column indices, forming what we refer to as matrix-framed data. These elements can take various forms, such as scalars, vectors, time series, matrices, or arrays. Existing data visualization methods aim to represent data elements of different groups without considering the underlying two-dimensional structure present in matrix-framed data. To address this limitation, we introduce a novel visualization method called Matrix t-SNE, designed to effectively embed matrix elements into a low-dimensional Euclidean space while preserving both row-wise and column-wise group structures. Our approach extends the classical t-SNE algorithm to accommodate matrix-framed data, providing a detailed algorithmic framework for embedding such data into low-dimensional representations. To demonstrate the effectiveness of Matrix t-SNE, we apply it to three real-world datasets: exergame, gene expression, and temperature. Our results show that Matrix t-SNE achieves more effective separation of elements according to latent row-wise and column-wise group structures compared to the classical t-SNE.
ISSN
2001-0370
Language
eng
URI
https://aurora.ajou.ac.kr/handle/2018.oak/38266
https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=105003195805&origin=inward
DOI
https://doi.org/10.1016/j.csbj.2025.04.019
Journal URL
https://www.sciencedirect.com/science/journal/20010370
Type
Article
Funding
This research was supported by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education (No. RS-2021-NR060141) and Global-Learning & Academic research institution for Master's\u22C5PhD students, and Postdocs (G-LAMP) Program of the National Research Foundation of Korea (NRF) grant funded by the Ministry of Education (No. RS-2023-00285390).
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Ahn, Soohyun안수현
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