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Suicidality is most centrally situated within network of depression symptom criteria in unipolar depression patients with mood stabilizer in Asiaoa mark
  • Yoon, Jin Woong ;
  • Kim, Eunkyung ;
  • Jeong, Narae ;
  • Kang, Minseok ;
  • Kim, Han Seul ;
  • Lee, Seonjae ;
  • Yoon, Hyung Jun ;
  • Kim, Seung Gon ;
  • Na, Euihyeon ;
  • Yang, Hyunju ;
  • Park, Joon Hyuk ;
  • Yang, Shu Yu ;
  • Lin, Shih Ku ;
  • Zhu, Xiaomin ;
  • Xiang, Yu Tao ;
  • Sim, Kang ;
  • Tan, Chay Hoon ;
  • Grover, Sandeep ;
  • Avasthi, Ajit ;
  • Kallivayalil, Roy Abraham ;
  • Maramis, Margarita M. ;
  • Chee, Kok Yoon ;
  • Pariwatcharakul, Pornjira ;
  • Oo, Tin ;
  • Kato, Takahiro A. ;
  • Javed, Afzal ;
  • Chong, Mian Yoon ;
  • Sartorius, Norman ;
  • Shinfuku, Naotaka ;
  • Park, Jeongsoo ;
  • Park, Seon Cheol
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dc.contributor.authorYoon, Jin Woong-
dc.contributor.authorKim, Eunkyung-
dc.contributor.authorJeong, Narae-
dc.contributor.authorKang, Minseok-
dc.contributor.authorKim, Han Seul-
dc.contributor.authorLee, Seonjae-
dc.contributor.authorYoon, Hyung Jun-
dc.contributor.authorKim, Seung Gon-
dc.contributor.authorNa, Euihyeon-
dc.contributor.authorYang, Hyunju-
dc.contributor.authorPark, Joon Hyuk-
dc.contributor.authorYang, Shu Yu-
dc.contributor.authorLin, Shih Ku-
dc.contributor.authorZhu, Xiaomin-
dc.contributor.authorXiang, Yu Tao-
dc.contributor.authorSim, Kang-
dc.contributor.authorTan, Chay Hoon-
dc.contributor.authorGrover, Sandeep-
dc.contributor.authorAvasthi, Ajit-
dc.contributor.authorKallivayalil, Roy Abraham-
dc.contributor.authorMaramis, Margarita M.-
dc.contributor.authorChee, Kok Yoon-
dc.contributor.authorPariwatcharakul, Pornjira-
dc.contributor.authorOo, Tin-
dc.contributor.authorKato, Takahiro A.-
dc.contributor.authorJaved, Afzal-
dc.contributor.authorChong, Mian Yoon-
dc.contributor.authorSartorius, Norman-
dc.contributor.authorShinfuku, Naotaka-
dc.contributor.authorPark, Jeongsoo-
dc.contributor.authorPark, Seon Cheol-
dc.date.issued2024-11-01-
dc.identifier.issn1876-2026-
dc.identifier.urihttps://aurora.ajou.ac.kr/handle/2018.oak/34445-
dc.identifier.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85203273276&origin=inward-
dc.description.abstractLithium and mood stabilizers are considered effective augmentation agents of antidepressants for treatment-resistant depression. Thus, this study aimed to estimate the network structure of depression symptom criteria among unipolar depression patients with mood stabilizers, using data from the Research on Asian Psychotropic Prescription Patterns for mood stabilizers (REAP-MS). We estimated a network of the 9 depression symptom criteria among 411 unipolar depression patients in Asia. Each of the depression symptom criteria was considered to be a dichotomous categorical variable. Suicidality (suicidal ideation or attempt) was the most centrally situated within the network of depression symptoms, followed by depressed mood, loss of energy, anhedonia and weight loss or gain. Contrastingly, concentration problem was the least interconnected. The depression symptom criteria were organized into 4 clusters by the community detection method. The findings suggest that suicidality may be one of the significant therapeutic target symptoms in unipolar depression patients with mood stabilizers.-
dc.description.sponsorshipThis work was supported by the government of the Republic of Korea (MSIT) and the National Research Foundation of Korea (NRF- 2024K2A9A2A08000106, FY2024).-
dc.language.isoeng-
dc.publisherElsevier B.V.-
dc.subject.meshAdult-
dc.subject.meshAntidepressive Agents-
dc.subject.meshAntimanic Agents-
dc.subject.meshAsia-
dc.subject.meshDepressive Disorder, Major-
dc.subject.meshDepressive Disorder, Treatment-Resistant-
dc.subject.meshFemale-
dc.subject.meshHumans-
dc.subject.meshMale-
dc.subject.meshMiddle Aged-
dc.subject.meshSuicidal Ideation-
dc.subject.meshSuicide, Attempted-
dc.subject.meshYoung Adult-
dc.titleSuicidality is most centrally situated within network of depression symptom criteria in unipolar depression patients with mood stabilizer in Asia-
dc.typeArticle-
dc.citation.titleAsian Journal of Psychiatry-
dc.citation.volume101-
dc.identifier.bibliographicCitationAsian Journal of Psychiatry, Vol.101-
dc.identifier.doi10.1016/j.ajp.2024.104197-
dc.identifier.pmid39250855-
dc.identifier.scopusid2-s2.0-85203273276-
dc.identifier.urlhttps://www.sciencedirect.com/science/journal/18762018-
dc.subject.keywordAsia-
dc.subject.keywordLithium-
dc.subject.keywordMood stabilizer-
dc.subject.keywordNetwork analysis-
dc.subject.keywordSuicidality-
dc.subject.keywordUnipolar depression-
dc.type.otherArticle-
dc.identifier.pissn1876-2018-
dc.description.isoatrue-
dc.subject.subareaPsychology (all)-
dc.subject.subareaPsychiatry and Mental Health-
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