Ajou University repository

3D Printing of Poly-ε-Caprolactone (PCL) Auxetic Implants with Advanced Performance for Large Volume Soft Tissue Engineering
  • Park, Jeong Hun ;
  • Park, Hyun Ji ;
  • Tucker, Sarah Jo ;
  • Rutledge, Sarah K. ;
  • Wang, Lizhen ;
  • Davis, Michael E. ;
  • Hollister, Scott J.
Citations

SCOPUS

0

Citation Export

DC Field Value Language
dc.contributor.authorPark, Jeong Hun-
dc.contributor.authorPark, Hyun Ji-
dc.contributor.authorTucker, Sarah Jo-
dc.contributor.authorRutledge, Sarah K.-
dc.contributor.authorWang, Lizhen-
dc.contributor.authorDavis, Michael E.-
dc.contributor.authorHollister, Scott J.-
dc.date.issued2023-06-12-
dc.identifier.issn1616-3028-
dc.identifier.urihttps://aurora.ajou.ac.kr/handle/2018.oak/33298-
dc.identifier.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85150589083&origin=inward-
dc.description.abstractA successful 3D printing of a novel 3D architected auxetic for large-volume soft tissue engineering is reported. The 3D auxetic design is analyzed through finite element (FE) simulation and created by selective laser sintering (SLS) of Poly-ε-caprolactone (PCL) for further in-depth mechanical and biological analysis. High initial flexibility and nonlinear stress–strain response to the uniaxial compression are achieved despite the use of PCL, which is one of the biomaterials that is clinically approved but has the disadvantage of having relatively stiff and linear mechanical properties. The high mass transport properties of the 3D auxetic are also demonstrated by not only high cell viability but also cell functionality within a cell-laden hydrogel in large sizes of the auxetic. The outstanding mechanical and biological performance of the 3D auxetic is a consequence of the synergistic effect of the novel architected auxetic design combined with the inherent printing characteristic of SLS. The current study demonstrates great potential of SLS-based printing of 3D auxetics toward the development of clinically viable 3D implants for the reconstruction of large-volume soft tissues.-
dc.description.sponsorshipJ.H.P. and H.\u2010J.P. contributed equally to this work. This research was supported by the US National Institutes of Health (NIH) (R01 HD 086201). In addition, H.\u2010J.P. acknowledges the support from American Heart Association (AHA) Postdoctoral Fellowship (837187).-
dc.language.isoeng-
dc.publisherJohn Wiley and Sons Inc-
dc.subject.mesh3-D printing-
dc.subject.mesh3D-printing-
dc.subject.meshAuxetics-
dc.subject.meshFinite element analyse-
dc.subject.meshFinite elements simulation-
dc.subject.meshLarge volumes-
dc.subject.meshMechanical analysis-
dc.subject.meshPerformance-
dc.subject.meshPoly(ε caprolactone)-
dc.subject.meshSoft tissue engineering-
dc.title3D Printing of Poly-ε-Caprolactone (PCL) Auxetic Implants with Advanced Performance for Large Volume Soft Tissue Engineering-
dc.typeArticle-
dc.citation.number24-
dc.citation.titleAdvanced Functional Materials-
dc.citation.volume33-
dc.identifier.bibliographicCitationAdvanced Functional Materials, Vol.33 No.24-
dc.identifier.doi2-s2.0-85150589083-
dc.identifier.scopusid2-s2.0-85150589083-
dc.identifier.urlhttp://onlinelibrary.wiley.com/journal/10.1002/(ISSN)1616-3028-
dc.subject.keyword3D printing-
dc.subject.keywordauxetics-
dc.subject.keywordfinite element analysis-
dc.subject.keywordselective laser sintering-
dc.subject.keywordsoft tissue engineering-
dc.type.otherArticle-
dc.identifier.pissn1616-301X-
dc.description.isoafalse-
dc.subject.subareaElectronic, Optical and Magnetic Materials-
dc.subject.subareaChemistry (all)-
dc.subject.subareaBiomaterials-
dc.subject.subareaMaterials Science (all)-
dc.subject.subareaCondensed Matter Physics-
dc.subject.subareaElectrochemistry-
Show simple item record

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Related Researcher

Park, Hyun Ji Image
Park, Hyun Ji박현지
College of Bio-convergence Engineering
Read More

Total Views & Downloads

File Download

  • There are no files associated with this item.