Clinical Significance of Surgical Resection Timing from Endoscopic Stenting for Leftsided Large Bowel Obstruction in Colorectal Cancer
DC Field | Value | Language |
---|---|---|
dc.contributor.advisor | 오승엽 | - |
dc.contributor.author | 윤순석 | - |
dc.date.accessioned | 2025-01-25T01:36:03Z | - |
dc.date.available | 2025-01-25T01:36:03Z | - |
dc.date.issued | 2023-02 | - |
dc.identifier.other | 32643 | - |
dc.identifier.uri | https://dspace.ajou.ac.kr/handle/2018.oak/24539 | - |
dc.description | 학위논문(석사)--아주대학교 일반대학원 :의학과,2023. 2 | - |
dc.description.tableofcontents | I. Introduction 1 <br>II. Methods 3 <br>III. Results 7 <br>IV. Discussion 12 <br>V. References 30 | - |
dc.language.iso | eng | - |
dc.publisher | The Graduate School, Ajou University | - |
dc.rights | 아주대학교 논문은 저작권에 의해 보호받습니다. | - |
dc.title | Clinical Significance of Surgical Resection Timing from Endoscopic Stenting for Leftsided Large Bowel Obstruction in Colorectal Cancer | - |
dc.type | Thesis | - |
dc.contributor.affiliation | 아주대학교 대학원 | - |
dc.contributor.alternativeName | Sunseok Yoon | - |
dc.contributor.department | 일반대학원 의학과 | - |
dc.date.awarded | 2023-02 | - |
dc.description.degree | Master | - |
dc.identifier.localId | T000000032643 | - |
dc.identifier.url | https://dcoll.ajou.ac.kr/dcollection/common/orgView/000000032643 | - |
dc.subject.keyword | Endoscopy | - |
dc.subject.keyword | Resection timing | - |
dc.subject.keyword | Stents | - |
dc.subject.keyword | colonic neoplasm | - |
dc.description.alternativeAbstract | The optimal interval between self-expanding metallic stent (SEMS) insertion and surgery remains controversial in malignant left-sided large-bowel obstruction (MLLO), especially with respect to oncologic aspects. <br>The aim of this study is to examine whether the time interval to surgery is related to oncologic outcomes. <br>A total of 149 patients underwent surgery after SEMS insertion. There were no significant differences between the early and late groups in the 5-year DFS (78.0% vs 72.4%; P = 0.513) and the OS (74.2% vs 75.7%; P = 0.864) rates in all MLLO. Subgroup analysis showed that there were significant differences between the two groups for DFS and OS in stage II MLLO. The multivariate Cox regression analysis in stage II MLLO demonstrated that the time to surgery was a prognostic factor for DFS (HR, 2.051; 95% CI, 1.528–42.136; P = 0.014) and for OS (HR, 4.947; 95% CI, 1.520–16.107; P = 0.008). <br>The time to surgery was demonstrated not to be a significant prognostic factor in all MLLO. However, it was a prognostic factor for patients with stage II MLLO. | - |
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