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Stereoselective Total Syntheses of Tsaokopyranols (–)-E, (–)-L, (+)-M, (+)- Jughopnin J, and (–)-Engelheptanoxide A
  • 손유희
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dc.contributor.advisor이동주-
dc.contributor.author손유희-
dc.date.issued2022-02-
dc.identifier.other31760-
dc.identifier.urihttps://aurora.ajou.ac.kr/handle/2018.oak/21182-
dc.description학위논문(석사)--아주대학교 일반대학원 :약학과,2022. 2-
dc.description.tableofcontentsI. Introduction 1 II. Results and Discussion 3 III. Conclusion 9 IV. Experimental Section 10 1. Materials and Methods 10 2. Full Experimental Procedures and Analytical Data of Compounds 11 V. References 28 VI. Appendix 31-
dc.language.isoeng-
dc.publisherThe Graduate School, Ajou University-
dc.rights아주대학교 논문은 저작권에 의해 보호받습니다.-
dc.titleStereoselective Total Syntheses of Tsaokopyranols (–)-E, (–)-L, (+)-M, (+)- Jughopnin J, and (–)-Engelheptanoxide A-
dc.typeThesis-
dc.contributor.affiliation아주대학교 일반대학원-
dc.contributor.alternativeNameYuhui Son-
dc.contributor.department일반대학원 약학과-
dc.date.awarded2022. 2-
dc.description.degreeMaster-
dc.identifier.uciI804:41038-000000031760-
dc.identifier.urlhttps://dcoll.ajou.ac.kr/dcollection/common/orgView/000000031760-
dc.subject.keyword(+)-Jughopnin J-
dc.subject.keyword(+)-Tsaokopyranol M-
dc.subject.keyword(–)-Engelheptanoxide A-
dc.subject.keyword(–)-Tsaokopyranol E-
dc.subject.keyword(–)-Tsaokopyranol L-
dc.subject.keywordDehydrogenative cycloetherification-
dc.subject.keywordDiastereoselectivity-
dc.subject.keywordNatural Products-
dc.subject.keywordtrans-2-Alkyl-6-aryl-3-
dc.subject.keyword6-dihydro2H-pyran-
dc.description.alternativeAbstractThe stereoselective total syntheses of naturally occurring bioactive 2,6-epoxydiarylheptanoids tsaokopyranols (–)-E, (–)-L, (+)-M, (+)-jughopnin J, and (–)-engelheptanoxide A have been accomplished in 4–6 steps starting from a chiral epoxide utilizing dehydrogenative cycloetherification and epimerization of trans- to cis-2-alkyl-6-aryl-3,6-dihydro-2H-pyran framework as the key steps. The absolute configuration of natural tsaokopyranol L was revised.-
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