Eun Jeong Lee 김은아 2024-08 33873 https://aurora.ajou.ac.kr/handle/2018.oak/38986 학위논문(석사)--의생명과학과,2024. 8 Ⅰ. INTRODUCTION 1_x000D_ <br> A. Monitoring methods of electrical brain activity 1_x000D_ <br> B. Evolution and challenges of MEAs 3_x000D_ <br> C. Enhancing chronic brain implants: Advances in flexible mesh probes 5_x000D_ <br> D. Soluble materials for deep brain implantation of flexible electronics 7_x000D_ <br> E. Aims 8_x000D_ <br>Ⅱ. MATERIALS AND METHODS 10_x000D_ <br> A. Procedure for fabricating the transient shuttle-based probe 10_x000D_ <br> B. Decreased rigidity of the transient shuttle-based probe 13_x000D_ <br> C. Brain tissue phantom using agarose gel 14_x000D_ <br> D. In vivo test using mice 14_x000D_ <br> E. Micro-CT imaging 15_x000D_ <br> F. Analysis method for Micro-CT Image 16_x000D_ <br> G. Tissue preparation and immunostaining 18_x000D_ <br> H. Analysis of immunostaining image 19_x000D_ <br>Ⅲ. RESULTS 21_x000D_ <br> A. Concept for the research and fabrication methods. 21_x000D_ <br> B. Mechanical characteristics of transient shuttle-based probes during insertion 32_x000D_ <br> C. Mechanical characteristics of transient shuttle-based probes during withdrawal. 39_x000D_ <br> D. In vivo test using mouse brains for insertion and withdrawal. 51_x000D_ <br> E. Histology studies of chronic implantation of the transient shuttle-based probe in mouse brains. 60_x000D_ <br>Ⅳ. CONCLUSIONS 69_x000D_ <br>REFERENCES 71_x000D_ <br>국문 요약 79_x000D_ eng The Graduate School, Ajou University 아주대학교 논문은 저작권에 의해 보호받습니다. Development of a Transient Shuttle-Based Probe for Chronic Monitoring of Wide Brain Areas Thesis 아주대학교 대학원 일반대학원 의생명과학과 2024-08 Master https://dcoll.ajou.ac.kr/dcollection/common/orgView/000000033873 mesh electronics neural probes transient electronics variable stiffness