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Showing results 1 to 10 of 13 (Search time: 0.0 seconds).

Recombinase-mediated cassette exchange-based screening of a CRISPR/Cas9 library for enhanced recombinant protein production in human embryonic kidney cells: Improving resistance to hyperosmotic stress
  • Shin, Seunghyeon;
  • Kim, Su Hyun;
  • Park, Jong Ho;
  • Lee, Jae Seong;
  • Lee, Gyun Min
  • 2022-07-01
  • Metabolic Engineering, Vol.72, pp.247-258
  • Academic Press Inc.
Streamlined Human Cell-Based Recombinase-Mediated Cassette Exchange Platform Enables Multigene Expression for the Production of Therapeutic Proteins
  • 2021-07-16
  • ACS Synthetic Biology, Vol.10, pp.1715-1727
  • American Chemical Society
Comprehensive Analysis of Genomic Safe Harbors as Target Sites for Stable Expression of the Heterologous Gene in HEK293 Cells
  • Shin, Seunghyeon;
  • Kim, Su Hyun;
  • Shin, Sung Wook;
  • Grav, Lise Marie;
  • Pedersen, Lasse Ebdrup;
  • Lee, Jae Seong;
  • Lee, Gyun Min
  • 2020-06-19
  • ACS Synthetic Biology, Vol.9, pp.1263-1269
  • American Chemical Society
Minimizing Clonal Variation during Mammalian Cell Line Engineering for Improved Systems Biology Data Generation
  • Grav, Lise Marie;
  • Sergeeva, Daria;
  • Lee, Jae Seong;
  • Marin De Mas, Igor;
  • Lewis, Nathan E.;
  • Andersen, Mikael Rørdam;
  • Nielsen, Lars Keld;
  • Lee, Gyun Min;
  • Kildegaard, Helene Faustrup
  • 2018-09-21
  • ACS Synthetic Biology, Vol.7, pp.2148-2159
  • American Chemical Society
Unraveling productivity-enhancing genes in Chinese hamster ovary cells via CRISPR activation screening using recombinase-mediated cassette exchange system
  • Baek, Minhye;
  • Kim, Che Lin;
  • Kim, Su Hyun;
  • la Cour Karottki, Karen Julie;
  • Hefzi, Hooman;
  • Grav, Lise Marie;
  • Pedersen, Lasse Ebdrup;
  • Lewis, Nathan E.;
  • Lee, Jae Seong;
  • Lee, Gyun Min
  • 2025-01-01
  • Metabolic Engineering, Vol.87, pp.11-20
  • Academic Press Inc.
A precise and sustainable doxycycline-inducible cell line development platform for reliable mammalian cell engineering with gain-of-function mutationsoa mark
  • 2024-11-01
  • Metabolic Engineering, Vol.86, pp.12-28
  • Academic Press Inc.
Revisiting the impact of genomic hot spots: C12orf35 locus as a hot spot and engineering targetoa mark
  • 2024-11-01
  • Biotechnology and Bioengineering, Vol.121, pp.3642-3649
  • John Wiley and Sons Inc
Hybrid cell line development system utilizing site-specific integration and methotrexate-mediated gene amplification in Chinese hamster ovary cells
  • 민홍기
  • 2023-02
  • The Graduate School, Ajou University
Improving the secretory capacity of CHO producer cells: The effect of controlled Blimp1 expression, a master transcription factor for plasma cells
  • Kim, Su Hyun;
  • Baek, Minhye;
  • Park, Sungje;
  • Shin, Seunghyeon;
  • Lee, Jae Seong;
  • Lee, Gyun Min
  • 2022-01-01
  • Metabolic Engineering, Vol.69, pp.73-86
  • Academic Press Inc.
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