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Enhancing the cytotoxicity of immunotoxins by facilitating their dissociation from target receptors under the reducing conditions of the endocytic pathway
Lee, Hyun Jin;
Chae, Byeong Ho;
Ko, Deok Han;
Lee, Seul Gi;
Yoon, Sang Rok;
Kim, Dae Seong;
Kim, Yong Sung
2024-10-01
International Journal of Biological Macromolecules, Vol.278
Elsevier B.V.
Expanding the Therapeutic Window of EGFR-Targeted PE24 Immunotoxin for EGFR-Overexpressing Cancers by Tailoring the EGFR Binding Affinity
oa mark
Jun, Sei Yong;
Kim, Dae Seong;
Kim, Yong Sung
2022-12-01
International Journal of Molecular Sciences, Vol.23
MDPI
Development of anti-integrin cyclic peptides and anti-EGFR monobody for specific delivery of payloads into targeted tumors
전세용
2023-02
The Graduate School, Ajou University
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Author
Kim, Dae Seong
2
Kim, Yong Sung
2
Chae, Byeong Ho
1
Jun, Sei Yong
1
Ko, Deok Han
1
Lee, Hyun Jin
1
Lee, Seul Gi
1
Yoon, Sang Rok
1
전세용
1
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Article
2
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1
Keyword
immunotoxin
2
affinity variants
1
anti-EGFR monobody
1
Cyclic peptide
1
Disulfide bond-dependent binding
1
EGFR
1
Endosome escape
1
Immunotoxin
1
integrin
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Monobody
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Date issued
2020 - 2025
3
Journal
International Journal of Biologic...
1
International Journal of Molecula...
1