An efficient reagent-free method for the synthesis of polysubstituted 4-quinolone from 2-substituted alkynoyl aryl-sulfonamide was developed. This developed method tolerates various functional groups and gives the corresponding 4-quinolones. We have successfully extended this method to the synthesis of dihydro-4-quinolones from 2-alkenoyl aryl sulfonamide derivatives.
This work was supported by National Research Foundation of Korea grants funded by the Korea Government (MSIT) (2023R1A2C2003964) and by \\u201CRegional Innovation Strategy (RIS)\\u201D through the National Research Foundation of Korea (NRF) funded by the Ministry of Education (MOE) (2021RIS-001). This research was also supported by S.S.\\u2019s Research Year of Chungbuk National University in 2023.
