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A study on the bio-applicability of aqueous-dispersed van der Waals 1-D material Nb2Se9 using poloxameroa mark
  • Chae, Sudong ;
  • Oh, Seungbae ;
  • Choi, Kyung Hwan ;
  • Lee, Jin Woong ;
  • Jeon, Jiho ;
  • Liu, Zhixiang ;
  • Wang, Cong ;
  • Lim, Changmo ;
  • Dong, Xue ;
  • Woo, Chaeheon ;
  • Asghar, Ghulam ;
  • Shi, Liyi ;
  • Kang, Joohoon ;
  • Kim, Sung Jae ;
  • Song, Si Young ;
  • Lee, Jung Heon ;
  • Yu, Hak Ki ;
  • Choi, Jae Young
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Publication Year
2021-12-01
Publisher
Nature Research
Citation
Scientific Reports, Vol.11
All Science Classification Codes (ASJC)
Multidisciplinary
Abstract
In this research, dispersion of a new type of one-dimensional inorganic material Nb2Se9, composed of van der Waals bonds, in aqueous solution for bio-application study were studied. To disperse Nb2Se9, which exhibits hydrophobic properties in water, experiments were carried out using a block copolymer (poloxamer) as a dispersant. It was confirmed that PPO, the hydrophobic portion of Poloxamer, was adsorbed onto the surface of Nb2Se9, and PEO, the hydrophilic portion, induced steric hinderance to disperse Nb2Se9 to a size of 10 nm or less. To confirm the adaptability of muscle cells C2C12 to the dispersed Nb2Se9 using poloxamer 188 as dispersant, a MTT assay and a live/dead assay were performed, demonstrating improvement in the viability and proliferation of C2C12 cells.
ISSN
2045-2322
Language
eng
URI
https://dspace.ajou.ac.kr/dev/handle/2018.oak/31758
DOI
https://doi.org/10.1038/s41598-020-80730-2
Fulltext

Type
Article
Funding
This research was supported by Leading University Project for International Cooperation through the National Research Foundation of Korea (NRF) funded by the Ministry of Education (MOE) (NRF-2019R1F1A1063170); and partially supported by NRF-2019R1A2C1006972. This work was supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIT). (No. 2020R1A2C2010984).
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Yu, Hak Ki류학기
Department of Materials Science Engineering
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