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DC Field | Value | Language |
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dc.contributor.author | Nguyen, Van Nghia | - |
dc.contributor.author | Park, Sang Jun | - |
dc.contributor.author | Qi, Sujie | - |
dc.contributor.author | Ha, Jeongsun | - |
dc.contributor.author | Heo, Seonye | - |
dc.contributor.author | Yim, Yubin | - |
dc.contributor.author | Baek, Gain | - |
dc.contributor.author | Lim, Chang Su | - |
dc.contributor.author | Lee, Dong Joon | - |
dc.contributor.author | Kim, Hwan Myung | - |
dc.contributor.author | Yoon, Juyoung | - |
dc.date.issued | 2020-10-04 | - |
dc.identifier.uri | https://dspace.ajou.ac.kr/dev/handle/2018.oak/31577 | - |
dc.description.abstract | Novel thiocarbonyl derivatives (NIS and CRNS) with excellent ROS generation abilities are synthesized and studied as potential photosensitizers for one- and two-photon excited photodynamic therapy. In particular,NIS-MeandCRNSdisplay outstanding phototoxicity toward HeLa cells under two-photon excitation (800 nm) with negligible dark toxicity. | - |
dc.description.sponsorship | This study was supported by grants from the National Research Foundation of Korea (NRF) funded by the Korean government (MSIP) (No. 2012R1A3A2048814 for J. Y. and No. 2019R1A2B5B03100278 for H. M. K.). | - |
dc.language.iso | eng | - |
dc.publisher | Royal Society of Chemistry | - |
dc.subject.mesh | Heavy atoms | - |
dc.subject.mesh | HeLa cell | - |
dc.subject.mesh | Photo-toxicity | - |
dc.subject.mesh | Ros generations | - |
dc.subject.mesh | Thiocarbonyl | - |
dc.subject.mesh | Two-photon excitations | - |
dc.subject.mesh | Two-photon excited | - |
dc.subject.mesh | Antineoplastic Agents | - |
dc.subject.mesh | Cell Proliferation | - |
dc.subject.mesh | Cell Survival | - |
dc.subject.mesh | Drug Design | - |
dc.subject.mesh | Drug Screening Assays, Antitumor | - |
dc.subject.mesh | HeLa Cells | - |
dc.subject.mesh | Humans | - |
dc.subject.mesh | Molecular Structure | - |
dc.subject.mesh | Optical Imaging | - |
dc.subject.mesh | Photochemotherapy | - |
dc.subject.mesh | Photosensitizing Agents | - |
dc.subject.mesh | Sulfhydryl Compounds | - |
dc.title | Design and synthesis of efficient heavy-atom-free photosensitizers for photodynamic therapy of cancer | - |
dc.type | Article | - |
dc.citation.endPage | 11492 | - |
dc.citation.startPage | 11489 | - |
dc.citation.title | Chemical Communications | - |
dc.citation.volume | 56 | - |
dc.identifier.bibliographicCitation | Chemical Communications, Vol.56, pp.11489-11492 | - |
dc.identifier.doi | 10.1039/d0cc04644b | - |
dc.identifier.pmid | 32857074 | - |
dc.identifier.scopusid | 2-s2.0-85091890742 | - |
dc.identifier.url | http://pubs.rsc.org/en/journals/journal/cc | - |
dc.description.isoa | false | - |
dc.subject.subarea | Catalysis | - |
dc.subject.subarea | Electronic, Optical and Magnetic Materials | - |
dc.subject.subarea | Ceramics and Composites | - |
dc.subject.subarea | Chemistry (all) | - |
dc.subject.subarea | Surfaces, Coatings and Films | - |
dc.subject.subarea | Metals and Alloys | - |
dc.subject.subarea | Materials Chemistry | - |
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