M13 bacteriophage (phage) nano- and microfibers were fabricated using electrospinning. Using liquid crystalline suspension of the phage, we successfully fabricated nano- and microscale pure phage fibers. Through a near field electrospinning process, we fabricated the desired phage fiber pattern with tunable direction and spacing. In addition, we demonstrated that the resulting phage fibers could be utilized as an electrostatic-stimulus responsive actuator. The near field electrospinning would be a very useful tool to design phage-based chemical sensors, tissue regenerative materials, energy generators, metallic and semiconductor nanowires in the future.
This work was supported by Tsinghua–Berkeley Shenzhen Institute, the National Research Foundation of Korea grant funded by the Korean Government (NRF-2014S1A2A2027641) and supported by a grant of the Korea Health Technology R&D Project through the Korea Health Industry Development Institute (KHIDI), funded by the Ministry of Health & Welfare, Republic of Korea (grant number: HI16C1067). Further support by Yuhan Inc. is appreciated.This work was supported by Tsinghua?Berkeley Shenzhen Institute, the National Research Foundation of Korea grant funded by the Korean Government (NRF-2014S1A2A2027641) and supported by a grant of the Korea Health Technology R&D Project through the Korea Health Industry Development Institute (KHIDI), funded by the Ministry of Health & Welfare, Republic of Korea (grant number: HI16C1067). Further support by Yuhan Inc. is appreciated.
