Polymeric micelles are versatile nanocarriers to carry hydrophobic moieties within the core in aqueous media. We report engineered polymeric micelles encapsulating highly photostable organic near-infrared (NIR) dye, IR788, for generating heat under NIR irradiation. In addition, the core of micelle is stabilized via semi-interpenetrating network formation (sIPN), which ensures stable loading under low temperature and enhances biocompatibility in cell experiment.
This work was supported by the National Research Foundation of Korea (NRF) funded by the Ministry of Science, ICT and Future Planning (NRF-2017M3D1A1039421) and by the Korea Polar Research Institute (PAP 2018).
