Fluorescent materials, the spontaneous light emission of irradiated materials, have some features of high sensitivity, technical simplicity, and fast response time for attractive and versatile tools such as drug discovery, cellular imaging, environmental analysis, electronic devices, and various medical applications. Despite of its widespread application in various fields, only few are researching novel fluorescent scaffolds that are harsh and tedious work. Many researchers are focusing on understanding and manipulating the conventional fluorophores. But still, it is needed the systematic change and design of fluorophore that can emphasize the utility and applicability of fluorescent materials. In the whole research, we focused on developing the new indolizine based fluorescent molecular frame to understand and to control systematically that can change its photophysical property like a kaleidoscope, called Kaleidolizine. The unique features of Kaleidolizine give a great potential for developing imaging techniques: 1) predictable photophysical property based on computational calculation covering full visible-color range 2) strong fluorescence emission in solid state that can consider lots of possibilities to apply on devices, and 3) great potential for detection of analytes in biological systems.
